Basic Information
VIS ID
TVIS44025945
Fusion event
HTLV-1-AUTS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
70194129/70729143 (Hg38)
End
70194129/70729143 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
AUTS2
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-222-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1183/Upstream/3614746; hsa-mir-10399/Downstream/578529;
Nearest TSS
ENST00000635602/Upstream/4; ENST00000483297/Downstream/34141;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/33442, chr7-CpG: 92/Downstream/60765
Upstream sequence
GCCACTTTCTGTTCTTTGTGAAAGCTAGAGCTGCTCTGCTCTTGAGAACAGCCATTTACAAAATGGGGCGAAAACGACGGCCACACCCTCCATCACTCTT
Downstream sequence
TTTCTCCTGGTGCTTTCCAGAGCCTTTGGAGACCTGTGCCGGGGGTGGGGCTTGGAGCTCCCGTGCCGATGGTTAAAGGTACCATGGCTGGGCCAGTGCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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