Basic Information
VIS ID
TVIS44025954
Fusion event
HTLV-1-DTX2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
76109996/76480679 (Hg38)
End
76109996/76480679 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA7J
Target gene
DTX2
miRNAs that regulate target gene
hsa-mir-20a-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6827-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-4707-5p ; hsa-mir-1225-3p ; hsa-mir-6798-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-6794-5p ; hsa-mir-940 ; hsa-mir-4716-3p ; hsa-mir-6893-5p ; hsa-mir-6808-5p
Nearest miRNA
hsa-mir-10525/Upstream/565410; hsa-mir-10399/Downstream/15723336;
Nearest TSS
ENST00000635602/Upstream/169; ENST00000467729/Downstream/11318;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/18501, chr7-CpG: 19/Downstream/19399
Upstream sequence
GGCAGGACGGGCTGGGCACCTGGCACCCCTACAGTGCCACCGTCTGCAGCTTCATCGAGCAGCAGTTTGTCCAGCAGAAGGGCCAACGTTTTGGGCTTGG
Downstream sequence
GAGCCTGGCCCACAGCATCCCCTTGGGCCAGGCAGACCCCTCGCTGGCCCCTTACATTATTGACCTCCCCAGCTGGACCCAGTTCCGCCAGGACACCGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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