Basic Information
VIS ID
TVIS44025968
Fusion event
HTLV-1-ASB4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
95123039/95493727 (Hg38)
End
95123039/95493727 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASB4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-6869-5p ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p
Nearest miRNA
hsa-mir-10525/Upstream/1776722; hsa-mir-10399/Downstream/725935;
Nearest TSS
ENST00000635602/Upstream/7826; ENST00000416502/Downstream/93818;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/58630, chr7-CpG: 15/Downstream/34127
Upstream sequence
GAGGTAACTTGGTATGTTACCTCCTTGTAACAAGAACAAGTGCATTTCTGTCCTGATCCCCCAACCCCCCAGTTCTTCTTGGAGGCCACCACTATAACCA
Downstream sequence
GTTTCGtgttctcagtgtttacaaatgtatttgcatatgatagcatagtttgtatactgtttggctccctgcttctctcattcagtaatatatcttgaga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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