Basic Information
VIS ID
TVIS44025973
Fusion event
HTLV-1-SPAG1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
101213295/100201067 (Hg38)
End
101213295/100201067 (Hg38)
Orient
-
Location type
Intronic
Target gene
SPAG1
miRNAs that regulate target gene
hsa-mir-106b-5p ; hsa-mir-101-3p ; hsa-mir-26b-5p ; hsa-mir-545-5p ; hsa-mir-582-5p ; hsa-mir-144-3p
Nearest miRNA
hsa-mir-12123/Upstream/664206; hsa-mir-10400/Downstream/181696;
Nearest TSS
ENST00000518652/Upstream/42639; ENST00000523302/Downstream/12020;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/42468, chr8-CpG: 95/Downstream/11782
Upstream sequence
ttttttttcagagccccccttaagaaagatttttttcagattttttttcttttgttgcttgtacttttgatatcatatataagaatccattgtcaaatcc
Downstream sequence
aaggtttaaaaacttactcctgtgttttatttctttttccttccttccttccttccttcctttttttagacaaggtcttactctgttgcccagactgaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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