Basic Information
VIS ID
TVIS44025986
Fusion event
HTLV-1-RP1L1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
10502030/10644520 (Hg38)
End
10502030/10644520 (Hg38)
Orient
-
Location type
Intronic
Target gene
RP1L1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-16-5p ; hsa-mir-5189-3p ; hsa-mir-4786-3p ; hsa-mir-1909-5p ; hsa-mir-4428
Nearest miRNA
hsa-mir-124-1/Upstream/741048; hsa-mir-10400/Downstream/22458;
Nearest TSS
ENST00000518652/Upstream/96935; ENST00000519925/Downstream/10582;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/31198, chr8-CpG: 38/Downstream/81786
Upstream sequence
CATGCCTGGCCCTGACTGTTGAAGGGTCACACCAGGCCACATGGGTGTAAGTCCCCCAGCCCTTAGCTGTGCAGAGAATTGTGATGGCTGAGAATTGATG
Downstream sequence
CCATCACAAGGTGACGCTGGACAGAGACCCAGGAACCAGTCCTTCCCCTCTCTAGTTTTGGCTAATTCATTCACCTCCCTGGACCTCAGCTCTTTAGTCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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