Basic Information
VIS ID
TVIS44025987
Fusion event
HTLV-1-OXR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
107738489/106726261 (Hg38)
End
107738489/106726261 (Hg38)
Orient
-
Location type
Exonic
Target gene
OXR1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-200b-3p ; hsa-mir-567 ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-4781-3p ; hsa-mir-144-3p ; hsa-mir-3144-3p ; hsa-mir-3915 ; hsa-mir-6730-3p ; hsa-mir-4689 ; hsa-mir-6858-5p ; hsa-mir-1224-5p ; hsa-mir-3928-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-586 ; hsa-mir-875-5p
Nearest miRNA
hsa-mir-12123/Upstream/2241796; hsa-mir-10400/Downstream/5917232;
Nearest TSS
ENST00000518652/Upstream/76; ENST00000521864/Downstream/13982;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/67898, chr8-CpG: 92/Downstream/1356366
Upstream sequence
AATTTATCTTTGACAGAGGAAGAATGCTTTTGAAAACAGTTCTTACGTGATTTTATGTAACTTAATTTGCCCTGGAAAGGAAATGTCTCGTCTCTGGTAT
Downstream sequence
GGGAAAAAAGGGAGAAGACATCAACCAATTAATCATAAATACACTCTGGTAAATCTTAGTCAATTATTTTAATTTGTATATATACTAGTCTTTTCATGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate