Basic Information
VIS ID
TVIS44026013
Fusion event
HTLV-1-ASAP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
131391593/130379347 (Hg38)
End
131391593/130379347 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASAP1
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-106b-5p ; hsa-mir-203a-3p ; hsa-mir-136-5p ; hsa-mir-544a ; hsa-mir-136-3p ; hsa-mir-432-5p ; hsa-mir-493-3p ; hsa-mir-208a-3p ; hsa-mir-208b-3p ; hsa-mir-27b-5p ; hsa-mir-3138 ; hsa-mir-3148 ; hsa-mir-4432 ; hsa-mir-4463 ; hsa-mir-4520-3p ; hsa-mir-4635 ; hsa-mir-4720-3p ; hsa-mir-499a-5p ; hsa-mir-6124 ; hsa-mir-6864-5p ; hsa-mir-8071 ; hsa-mir-8087 ; hsa-mir-875-3p
Nearest miRNA
hsa-mir-1204/Upstream/370894; hsa-mir-10400/Downstream/2667134;
Nearest TSS
ENST00000518652/Upstream/38410; ENST00000523318/Downstream/7530;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/20276, chr8-CpG: 141/Downstream/63655
Upstream sequence
cccatacctggccctagcatcgcttctattgggctgtccctgagttgtatcctttataataaaccagtaatagtaagtattttcctgagttctgacgaga
Downstream sequence
tcaagcgtgttcagggtggtatggctgtagatgtattttcctgagttctgtgagttctagccaatcatcacacttgagaaggaaattgtggaaacctctc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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