Basic Information
VIS ID
TVIS44026034
Fusion event
HTLV-1-TRAPPC9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
140781441/139769198 (Hg38)
End
140781441/139769198 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRAPPC9
miRNAs that regulate target gene
hsa-mir-30e-5p ; hsa-mir-196a-5p ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-6873-5p ; hsa-mir-583
Nearest miRNA
hsa-mir-1204/Upstream/4964253; hsa-mir-10400/Downstream/963366;
Nearest TSS
ENST00000518652/Upstream/66142; ENST00000518354/Downstream/37035;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/36943, chr8-CpG: 20/Downstream/277989
Upstream sequence
gtctgtagtgctttgttaGAAAAACTACTAcagtaaccctgttatcctcgggggcaggttccaagacccccagtggacggctgaaacctcagatagtact
Downstream sequence
gaaccctatatacactatgttttttcctcgacatacatacctatgataaagtttaacttatgtattaggcatagtgagagacttacaatattaactaata
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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