Basic Information
VIS ID
TVIS44026054
Fusion event
HTLV-1-ARHGEF10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
1783509/1835343 (Hg38)
End
1783509/1835343 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGEF10
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-3674/Upstream/18036; hsa-mir-10400/Downstream/241246;
Nearest TSS
ENST00000518652/Upstream/9232; ENST00000382795/Downstream/23412;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/3688, chr8-CpG: 50/Downstream/6470
Upstream sequence
AGGGCTGAGCAGTAAGTGAAGAGCGGGGCACTTCACAGGCACAGAGCCTGTCCCTGCCCCAGGTGCATCTCTGAAACCACGCGGCAGCCCTGTGAGTCGG
Downstream sequence
TGCCGTCCCTGTGCAGCTGAGGCCGTGGGGGTACAGGCAGGTCAAGGGCCTGTGTGGCTGGGAAGTGCTGGGCTGGGGCAGATGCAGACAGGCTCCCGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate