Basic Information
VIS ID
TVIS44026150
Fusion event
HTLV-1-RAD54B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
95451106/94438878 (Hg38)
End
95451106/94438878 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
RAD54B
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-346
Nearest miRNA
hsa-mir-12123/Upstream/522759; hsa-mir-10400/Downstream/634033;
Nearest TSS
ENST00000518652/Upstream/1926; ENST00000521010/Downstream/29136;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/176451, chr8-CpG: 36/Downstream/35824
Upstream sequence
agcaaaattttttaagacttaaaatgccaagagtgaggccaggctcagtggcacatgggcctgtaatccaacagttttgagaggccaaggattacttgag
Downstream sequence
cacatgagttcaagaccagaccgggcaacatggagaaaccccatgtctacaaaaaatacaaaaattagccaggtgtggtggcatatgcctgtagttccag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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