Basic Information
VIS ID
TVIS44026160
Fusion event
HTLV-1-VPS13B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
100786638/99774410 (Hg38)
End
100786638/99774410 (Hg38)
Orient
-
Location type
Intronic
Target gene
VPS13B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-30e-5p ; hsa-mir-186-5p ; hsa-mir-3613-5p ; hsa-mir-4494 ; hsa-mir-499b-5p ; hsa-mir-4705
Nearest miRNA
hsa-mir-12123/Upstream/237549; hsa-mir-10400/Downstream/608353;
Nearest TSS
ENST00000518652/Upstream/53542; ENST00000493587/Downstream/24777;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/760639, chr8-CpG: 35/Downstream/119019
Upstream sequence
CTAGCACTAATGCTTACTGGAGTATGATTTTATGATTCAGGAGCTACTGTATATACCTAAAAATATGTCTAACCATTGCTTTGTGCATTCAATTTAGGAA
Downstream sequence
AAGTGAAGAATCAATCAATTTGTTATAAGTAAAGATTGTATTAGATACTCATGATGTTTTAGCAACCTTTTGTAATATGTTATAATATTTGCCACTCTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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