Basic Information
VIS ID
TVIS44026176
Fusion event
HTLV-1-WHRN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
GRCh37/hg19
Start
117183687/114421407 (Hg38)
End
117183687/114421407 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
WHRN
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7a-1/Upstream/211878; hsa-mir-12126/Downstream/5823572;
Nearest TSS
ENST00000422679/Upstream/22904; ENST00000473413/Downstream/4664;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/22623, chr9-CpG: 165/Downstream/82781
Upstream sequence
TGCTGTGGGCCAGTGCCGAGCTGGGGGCTCCTGACCCCTGCCCCAGAGCCCTTGCCAGGCAAGATAGTCACCTGACTCCTGGCACTCCAGCCTGATTTGC
Downstream sequence
CCTCAGGGCTTCGGGCTGCTGAAGTCAGAGCCAGCAAGGACCCCAGGCCATTTTATCCAGAAACTGAAGACCAGAAAGGCTGGGGCTCAAACCTAGACCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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