Basic Information
VIS ID
TVIS44026177
Fusion event
HTLV-1-TNC integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
117832549/115070270 (Hg38)
End
117832549/115070270 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9E ; FRA9B
Target gene
TNC
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-20b-3p ; hsa-mir-3137 ; hsa-mir-3606-3p ; hsa-mir-3686 ; hsa-mir-4652-3p ; hsa-mir-4732-5p ; hsa-mir-4743-3p ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-6832-5p
Nearest miRNA
hsa-let-7a-1/Upstream/860741; hsa-mir-12126/Downstream/5174709;
Nearest TSS
ENST00000422679/Upstream/5358; ENST00000477580/Downstream/3371;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/458474, chr9-CpG: 77/Downstream/1083813
Upstream sequence
taagtttcacaaggaaacctagagcagcttgaaggggtagatcaggatgggggtgcctttttaggctggtagtcagagaagccctctgttctgggtcata
Downstream sequence
tctgagctgctgagtgaaatgagggagcacgctctgtgaagtgctgggaaaagagtggtatccagggagtgggagcagcacactccaaagcccgagggtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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