Basic Information
VIS ID
TVIS44026206
Fusion event
HTLV-1-ADAMTS13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.2
Reference genome
GRCh37/hg19
Start
136308791/133443670 (Hg38)
End
136308791/133443670 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAMTS13
miRNAs that regulate target gene
hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-6749-3p ; hsa-mir-296-5p ; hsa-mir-4745-3p ; hsa-mir-1538 ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-181c-3p
Nearest miRNA
hsa-let-7a-1/Upstream/391611; hsa-mir-126/Downstream/935741;
Nearest TSS
ENST00000422679/Upstream/21345; ENST00000371910/Downstream/11978;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/13554, chr9-CpG: 75/Downstream/15884
Upstream sequence
GGGCTAGGTGGGGCTGGGAGAGGGCCTTCCTGGCAGAGCTCGTCCCTGCGCTGAGCCCCCATCCTTCTGAGAATCCCCTCCTCCTGAGGCCTCCGGCGGG
Downstream sequence
GCCTCACCATCCAGGGTGATGGGCAGTGTCACCTGGCGGTTGTAAGTGCTGCTGTCAGAGTTCcttactacccaggagagcctgggcccattgtttccct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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