Basic Information
VIS ID
TVIS44026237
Fusion event
HTLV-1-UBE2R2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
33911793/33911795 (Hg38)
End
33911793/33911795 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBE2R2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-103a-3p ; hsa-mir-93-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/443860; hsa-let-7a-1/Downstream/1696299;
Nearest TSS
ENST00000422679/Upstream/93000; ENST00000448245/Downstream/17040;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/93493, chr9-CpG: 75/Downstream/136846
Upstream sequence
CACAGATTTCCTCTGCTTTGCCTGCCAGTTAGCAGCTTGTTTCTTAGTGCTGaaaaaaatttttttttatttttCTTAAATGCCTTTTATGAAAACTATC
Downstream sequence
AATAAAAAATTTATATCTCTATTCCCCCAAGGTCTTAAATTTAATTGTATCAGAAAAATTTTAAGGGAGGGAGAATTTGAAATCTGATTGTACTATCTTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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