Basic Information
VIS ID
TVIS44026248
Fusion event
HTLV-1-SLC25A51 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
37898804/37898807 (Hg38)
End
37898804/37898807 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC25A51
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-222-3p ; hsa-mir-643 ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-498 ; hsa-mir-4284 ; hsa-mir-6722-5p ; hsa-mir-6778-3p ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1281 ; hsa-mir-4485-5p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p
Nearest miRNA
hsa-mir-101-2/Upstream/1005276; hsa-let-7a-1/Downstream/3030203;
Nearest TSS
ENST00000422679/Upstream/40327; ENST00000422554/Downstream/5303;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/97241, chr9-CpG: 85/Downstream/4826
Upstream sequence
actctgtctcaaaaataaataaataaataaaataaaaaTGAATTTCATTTTTCTAGTCAACTGATAAGTCAAACTGAGAGAATTTTCAAACATGGGAAGG
Downstream sequence
AAATATACATTTATTATTGTTGTACTGAAGTTCAATCACCTCCACACCTTCCCACCGCCAATAACTCAAGAGTCTATCTTAAACTTTGGTCAAATGCTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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