Basic Information
VIS ID
TVIS44026267
Fusion event
HTLV-1-PCSK5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
78727845/76112929 (Hg38)
End
78727845/76112929 (Hg38)
Orient
-
Location type
Intronic
Target gene
PCSK5
miRNAs that regulate target gene
hsa-mir-107
Nearest miRNA
hsa-mir-101-2/Upstream/5302845; hsa-let-7a-1/Downstream/7856819;
Nearest TSS
ENST00000422679/Upstream/16952; ENST00000455778/Downstream/75710;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/220193, chr9-CpG: 101/Downstream/280792
Upstream sequence
GAAGGGTTGTAGGGGGTGCAGGACTTGGATGAAAATAAAAATGCCCAGCTTTGATGATTCAAATTGGAACATTGGTTCCATAGAAATTTGTATCCTCCAC
Downstream sequence
GACACCTAAGCATAATGTTTTGAACAAGGTCCATTCTCAACAAATATTAAATTAATtcgtctagtccaaccttaccttttgtacaatggaactgagtcct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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