Basic Information
VIS ID
TVIS44026321
Fusion event
HTLV-1-GABBR2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
101163672/98401390 (Hg38)
End
101163672/98401390 (Hg38)
Orient
+
Location type
Intronic
Target gene
GABBR2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-129-5p ; hsa-mir-34c-5p ; hsa-mir-144-5p ; hsa-mir-599
Nearest miRNA
hsa-let-7a-1/Upstream/172173; hsa-mir-12126/Downstream/8199538;
Nearest TSS
ENST00000422679/Upstream/12503; ENST00000610463/Downstream/114909;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/145091, chr9-CpG: 230/Downstream/305907
Upstream sequence
TACTTTCCACAtgagagggaatgagttccccatcactggaggcattcaagcagtgggaatgTTGTATAAGAGAATCAGGGCTCCCTTCAACATGGAGAGT
Downstream sequence
CGATGGCTCAATGAAACCCAATACCTGTAAAATATGCTGTCTTTTGGGCCACCTTTCTTAGGCTCCCTGAAAGGCAAATCCTGGAACATGAGGGCTGGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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