Basic Information
VIS ID
TVIS44026353
Fusion event
HTLV-1-ATRNL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
117490673/115731163 (Hg38)
End
117490673/115731163 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ATRNL1
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-379-3p ; hsa-mir-3613-3p ; hsa-mir-3163 ; hsa-mir-577 ; hsa-mir-6771-3p ; hsa-mir-4282 ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac
Nearest miRNA
hsa-mir-107/Upstream/1556984; hsa-mir-202/Downstream/1096325;
Nearest TSS
ENST00000439456/Upstream/263989; ENST00000449616/Downstream/178188;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/636828, chr10-CpG: 18/Downstream/394139
Upstream sequence
agggtgggcctgcctttcccagcccactgactcaaatgttaatcttctttggcacatcgtcgcagacacacccaggatccatacattgcatccttcaatg
Downstream sequence
caatcaagttgacactcagtattaaccgtcacaATCAGTCTCCAGCCTTAGGCTGGCACTTGACTGGTTCTGCTGCTTTCCTGCCCCACAGCAGGTGGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate