Basic Information
VIS ID
TVIS44026355
Fusion event
HTLV-1-SHTN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
118878283/117118772 (Hg38)
End
118878283/117118772 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
SHTN1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-106b-5p
Nearest miRNA
hsa-mir-107/Upstream/291204; hsa-mir-202/Downstream/48906;
Nearest TSS
ENST00000439456/Upstream/113195; ENST00000334549/Downstream/7814;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/113137, chr10-CpG: 62/Downstream/7282
Upstream sequence
gataaagaaaatgtggtatacatgtgttctcacttataagtgggagctgaatgatgagaacacatggacacatgagggggaacaacacacactggggcct
Downstream sequence
gttggaggatgggtctgggaggagggagagcatcaggaagaagagctaatggattccgtgctttatacctgggtgatgcgatgatcagtgcagcaaacca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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