Basic Information
VIS ID
TVIS44026367
Fusion event
HTLV-1-CPXM2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
125506568/123747052 (Hg38)
End
125506568/123747052 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
CPXM2
miRNAs that regulate target gene
hsa-mir-6751-3p ; hsa-mir-4762-3p ; hsa-mir-6873-3p ; hsa-mir-4539 ; hsa-mir-4695-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-6787-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6877-3p ; hsa-mir-6819-3p
Nearest miRNA
hsa-mir-107/Upstream/1329985; hsa-mir-202/Downstream/1285731;
Nearest TSS
ENST00000439456/Upstream/80697; ENST00000446888/Downstream/29618;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/79926, chr10-CpG: 25/Downstream/110489
Upstream sequence
TTCGGCCTTTGCTGTGACCACATACTCTCCAGGGTTCAGGAGGCGCCAGTAATCCCCATCGTTGGCTGTGAAAAAGAAAACCAGGGGAGACTCAGAGCAG
Downstream sequence
CTCTTGCTAATGCAGATCCCGCCAGCCCTCCTCCAAGACCAGCTCCCTGGGCCAGAGAGAGACTCTCAGGCTGGCAACGTGGAATCCGAGCTCCTGCAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate