Basic Information
VIS ID
TVIS44026390
Fusion event
HTLV-1-FRMD4A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
GRCh37/hg19
Start
13950048/13908048 (Hg38)
End
13950048/13908048 (Hg38)
Orient
+
Location type
Intronic
Target gene
FRMD4A
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-218-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-3155a/Upstream/1182695; hsa-mir-107/Downstream/475152;
Nearest TSS
ENST00000439456/Upstream/178665; ENST00000446193/Downstream/64321;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/15864, chr10-CpG: 135/Downstream/695705
Upstream sequence
tgaggtcaggagttcacgaccagcctggccaacatggtaaaaccccgtctctactaaaaatacaaaattagccaggcatggtggcgggcacctgtaatcc
Downstream sequence
cagctactcaggaggctgaggcaggagaatcgcttgaaccctggaggcagaggttgcagtgagccaagatcgtgccactgcactccagcctggacaagaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate