Basic Information
VIS ID
TVIS44026397
Fusion event
HTLV-1-NEBL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.31
Reference genome
GRCh37/hg19
Start
21091194/20802265 (Hg38)
End
21091194/20802265 (Hg38)
Orient
+
Location type
Intronic
Target gene
NEBL
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-7856-5p ; hsa-mir-4477b ; hsa-mir-4684-5p ; hsa-mir-6892-5p ; hsa-mir-942-5p ; hsa-mir-7845-5p ; hsa-mir-4475 ; hsa-mir-6507-3p ; hsa-mir-6883-3p ; hsa-mir-3156-3p ; hsa-mir-324-5p ; hsa-mir-3162-3p ; hsa-mir-4301 ; hsa-mir-140-3p
Nearest miRNA
hsa-mir-1265/Upstream/250219; hsa-mir-107/Downstream/694297;
Nearest TSS
ENST00000439456/Upstream/710481; ENST00000417845/Downstream/13560;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/984248, chr10-CpG: 149/Downstream/370934
Upstream sequence
AAACTGCAAGTTAAGGAAAACCAAAGAAACACAAAGTAATACCGGGAAGCAGATACACATTGCAGGCAATGAACTAGAGGCAAACACAAAGATCAAAGGA
Downstream sequence
AACCTCACAGTGAAATAAGCTGAAATCATCAGGATCCTTTTCACCAAAGGAGCTGTGTGTCAAATAAAATATAAGTTAAGCGAATCTAATACCAAAAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate