Basic Information
VIS ID
TVIS44026404
Fusion event
HTLV-1-MYO3A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
26420356/26131427 (Hg38)
End
26420356/26131427 (Hg38)
Orient
+
Location type
Intronic
Target gene
MYO3A
miRNAs that regulate target gene
hsa-mir-409-3p ; hsa-mir-6894-3p ; hsa-mir-4276 ; hsa-mir-3127-5p ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-4763-5p ; hsa-mir-3692-5p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-3918 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p
Nearest miRNA
hsa-mir-1265/Upstream/1855646; hsa-mir-107/Downstream/2157831;
Nearest TSS
ENST00000439456/Upstream/179327; ENST00000477691/Downstream/34415;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/196334, chr10-CpG: 40/Downstream/80251
Upstream sequence
GATCAAGAAACTACAGTAAAACATTTTTTTGTGAAAGAATTTATGATGGTGACCCAATCTATAGCATGCAGAGTAGATAGTTTTATGTTTCTTGGAATTG
Downstream sequence
TTTCCACCTGTTTGCATTACCTTTGAAACATTTTCCTAAATCCAGGAATCTCTATTATCCACTCACTGGCAGCTATACCTCCTTTCTCTTATAGCCTGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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