Basic Information
VIS ID
TVIS44026407
Fusion event
HTLV-1-ANKRD26 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
27294138/27005209 (Hg38)
End
27294138/27005209 (Hg38)
Orient
-
Location type
UTR3
Target gene
ANKRD26
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-4480 ; hsa-mir-4786-3p ; hsa-mir-802 ; hsa-mir-548at-5p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n
Nearest miRNA
hsa-mir-1265/Upstream/2729428; hsa-mir-107/Downstream/1284049;
Nearest TSS
ENST00000439456/Upstream/144122; ENST00000477034/Downstream/9470;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/143909, chr10-CpG: 51/Downstream/94937
Upstream sequence
GTTTCTCCCTGAGAACAGCTATATAAATCAGTGCTTAAAATTAAAATTATGTAAATTTGATGGCACTGTAACAATTGTAATACATCCAAACATGAACAAT
Downstream sequence
GACCACAGTTCCTGCACAACAAAATGATGTCTAAGTCCAATTAGACATCTACCACTACATATAGTGATAAAAATTACAAAATACAAATAAGCCATCAATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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