Basic Information
VIS ID
TVIS44026453
Fusion event
HTLV-1-WASHC2A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
51891072/50131312 (Hg38)
End
51891072/50131312 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
WASHC2A
Nearest miRNA
hsa-mir-1265/Upstream/1145725; hsa-mir-107/Downstream/1168261;
Nearest TSS
ENST00000439456/Upstream/11662; ENST00000437213/Downstream/67834;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/62785, chr10-CpG: 29/Downstream/21541
Upstream sequence
GGCTGAAGATAGGTAAGAGATGGACTAATTATTTTAGTGAAGTAACTCTTTCCTATGATAGTCATCAAAGAATTTGAAGGCACCCAGAGTTTGACGTTTA
Downstream sequence
AGTATAATTTAACTTTGATCTCAGTGCACCTCACCAATCATCTGTGACACACCCCGGTGTTATGAAAGGAGGTTTGATCAGAAATGACCTCACGTGCTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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