Basic Information
VIS ID
TVIS44026472
Fusion event
HTLV-1-C10orf105 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
73490102/71730345 (Hg38)
End
73490102/71730345 (Hg38)
Orient
+
Location type
Intronic
Target gene
C10orf105
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-676-5p ; hsa-mir-3667-3p ; hsa-mir-5193 ; hsa-mir-5088-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-539-5p ; hsa-mir-432-5p ; hsa-mir-520g-5p ; hsa-mir-5007-5p
Nearest miRNA
hsa-mir-1265/Upstream/4326935; hsa-mir-107/Downstream/60402;
Nearest TSS
ENST00000439456/Upstream/10524; ENST00000642965/Downstream/7479;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/68400, chr10-CpG: 49/Downstream/42989
Upstream sequence
GAAGttcattccgaaacaagtaatgtttgagcacctgccacgcgccaggtgctgtgcaaggtggtggtcacagtgacccaccagacaggcctggggtcct
Downstream sequence
agagggagctcacagCAGGCCCAGGAAAGCAGTGACCACACAAGGCGGCCACAGTGGGCCAAGCCCTGGGCTTCCCAGCCTCCACCCCACCCTGACCTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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