Basic Information
VIS ID
TVIS44026482
Fusion event
HTLV-1-KCNMA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
79336668/77576910 (Hg38)
End
79336668/77576910 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
KCNMA1
miRNAs that regulate target gene
hsa-mir-211-5p ; hsa-mir-218-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1265/Upstream/2024357; hsa-mir-107/Downstream/8687784;
Nearest TSS
ENST00000439456/Upstream/77940; ENST00000600739/Downstream/60425;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1464363, chr10-CpG: 220/Downstream/59427
Upstream sequence
ATCAAGCCTCGAGATGCTGGTAACCTGTCCAAGTCATTTAACGGGAGGAGGAAGGACGACAATGGCTTACACTGTTTCCCATGCaccatgtgttaggcac
Downstream sequence
tgtgtgaaatgctctgcaagtattatttcattcaattctcactgaaatcccatgaaatgctcattgctatggcaccacagtttaacaggaaagaatggag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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