Basic Information
VIS ID
TVIS44026500
Fusion event
HTLV-1-EXOC6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
94703752/92943995 (Hg38)
End
94703752/92943995 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
EXOC6
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-31-5p ; hsa-mir-4668-3p ; hsa-mir-6739-3p ; hsa-mir-6853-3p ; hsa-mir-1206
Nearest miRNA
hsa-mir-107/Upstream/3351168; hsa-mir-1287/Downstream/3120320;
Nearest TSS
ENST00000439456/Upstream/15621; ENST00000458552/Downstream/53479;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/94713, chr10-CpG: 255/Downstream/116274
Upstream sequence
tctgatcgccctaccctctggtaacctataaatcagaaatcaggcttctctctacttctgtgagtgtgactgttttagattcctcatataagtgagatta
Downstream sequence
tgcagtatttgacttctgtgcctagcttatgtcacttagcataatgtcctcaaggttcatccttgttgttgcaaatgacagaatttccctcttttatagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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