Basic Information
VIS ID
TVIS44026503
Fusion event
HTLV-1-BLNK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
97972940/96213184 (Hg38)
End
97972940/96213184 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
BLNK
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-107/Upstream/148785; hsa-mir-1287/Downstream/615485;
Nearest TSS
ENST00000439456/Upstream/2881; ENST00000630152/Downstream/14313;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/82529, chr10-CpG: 20/Downstream/171358
Nearest cancer related gene
BLNK(TSG, No orient, 0)
Upstream sequence
TAAAGCCCTGTTGGTGATTCTTTAAATATTTAATACAACCAGTGTTTGAGGACTCATTCACCCTCTCAACCAACTGACCCCTCCACAGTCTCGGCACCTC
Downstream sequence
CCCTGAGCCAGATCCTGGGGTAGGCCCTGGAAACAGCTGTGAGCAAATAAAGACAGAAATCTCAGGGCATGTGCAGGGCACTAGAGGGATCTGTCCCAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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