Basic Information
VIS ID
TVIS44026544
Fusion event
HTLV-1-CCDC15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
124885312/125015416 (Hg38)
End
124885312/125015416 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC15
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-1324 ; hsa-mir-218-1-3p ; hsa-mir-4756-3p ; hsa-mir-659-3p ; hsa-mir-7977
Nearest miRNA
hsa-let-7a-2/Upstream/1633904; hsa-mir-3167/Downstream/1973042;
Nearest TSS
ENST00000527297/Upstream/61295; ENST00000524471/Downstream/22040;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/60983, chr11-CpG: 83/Downstream/47418
Upstream sequence
attttgttttgccaaggatatatcacttttactaatcagtaaaaagaaaaaacacaattcaccaatattaggaatggaaagggaaccattactacagagc
Downstream sequence
ctacagacattaaatcacagtaagagaacattataaacaactttacattttaaaaatttgacaattttaataaaataaactcctatggggataaaacaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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