Basic Information
VIS ID
TVIS44026551
Fusion event
HTLV-1-ARHGAP32 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
129024476/129154581 (Hg38)
End
129024476/129154581 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARHGAP32
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-423-5p ; hsa-mir-183-5p ; hsa-mir-93-5p ; hsa-mir-6082 ; hsa-mir-139-5p ; hsa-mir-4799-5p ; hsa-mir-6501-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-3119
Nearest miRNA
hsa-let-7a-2/Upstream/632132; hsa-mir-4697/Downstream/1512154;
Nearest TSS
ENST00000527297/Upstream/87768; ENST00000605151/Downstream/9764;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/263243, chr11-CpG: 194/Downstream/124021
Upstream sequence
actggcccttgaccaacaagtggataaagaaaatgtggtatatatacactacagaatactactcagccacaaaaaggaatgaaataatggcatccgtagc
Downstream sequence
aacctggatgggtttggagaccattattttaagtgaagtaactcaggaatggaaaaccaaataccgttatgttcttacttataagtgggagctaagctat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate