Basic Information
VIS ID
TVIS44026552
Fusion event
HTLV-1-ADAMTS15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
130342187/130472292 (Hg38)
End
130342187/130472292 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADAMTS15
miRNAs that regulate target gene
hsa-mir-137 ; hsa-mir-4540 ; hsa-mir-6723-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-6858-3p
Nearest miRNA
hsa-let-7a-2/Upstream/1949843; hsa-mir-4697/Downstream/194443;
Nearest TSS
ENST00000527297/Upstream/23318; ENST00000317019/Downstream/200664;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/21989, chr11-CpG: 51/Downstream/769
Upstream sequence
GCCCAGGTGCTGGTGATGGAAAGGCCTAGATGGCTGTCCTGGAGCCTTGACTGTGCCCCTGGACACGTCGCCCTCTCCTGAGCCCCTGGGTGGTGATGCG
Downstream sequence
AAGGGAGGATGCCCAGCCCTGTCTCTGGGAGCTCGGGCACCAGGGACGGATGGCATTCCAGGCTGTGCTTTGCAGGGACCTGTGGTGGCAAGGCCACGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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