Basic Information
VIS ID
TVIS44026556
Fusion event
HTLV-1-ARNTL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
13379004/13357457 (Hg38)
End
13379004/13357457 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARNTL
miRNAs that regulate target gene
hsa-mir-494-3p ; hsa-mir-142-3p ; hsa-mir-335-5p ; hsa-mir-3674 ; hsa-mir-6844 ; hsa-mir-6073 ; hsa-mir-6505-3p ; hsa-mir-4280 ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-513a-5p ; hsa-mir-3607-3p ; hsa-mir-4494 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-210/Upstream/1193690; hsa-let-7a-2/Downstream/2612076;
Nearest TSS
ENST00000527297/Upstream/579; ENST00000534102/Downstream/977;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/78411, chr11-CpG: 82/Downstream/105269
Nearest cancer related gene
ARNTL(TSG, No orient, 0)
Upstream sequence
AAGTTTTTCCCCAGTCTTCAGCAGAGAACGTCTTCCTGACTGGAGCGCCCTCCGCAGGAGACATGGCTCAGTGATTTGGTTCCTGGGCTGGGACTTGCCT
Downstream sequence
CTGTCAGGGGCCCCTATTGCACTGCGAGTTGCAACTGAATGCACCACATGGGGCATGCTCGGTGTCTCGAGTAGATTCTCTGCCTGGGTCTGTCCTGCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate