Basic Information
VIS ID
TVIS44026561
Fusion event
HTLV-1-CYP2R1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
14912462/14890916 (Hg38)
End
14912462/14890916 (Hg38)
Orient
+
Location type
Intronic
Target gene
CYP2R1
miRNAs that regulate target gene
hsa-let-7a-5p
Nearest miRNA
hsa-mir-210/Upstream/2727149; hsa-let-7a-2/Downstream/1078617;
Nearest TSS
ENST00000527297/Upstream/385; ENST00000324229/Downstream/576;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/245788, chr11-CpG: 68/Downstream/438
Upstream sequence
ggattataggcgtgagccaccgcgcccggGCACCTAGACCAATCCTTGTAAAAATTGGTTTAAGTAAGGATTTAAGGTCAAACCTGAAATACCACAGTTG
Downstream sequence
CCAAACATCCCTGTACTTTTCCTTCAAAACACTGACCACAGCCTGTGGCCGATAATGAGATTAGTTTTCTCTCTCCCACTCATCTGCCAACTCCTTAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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