Basic Information
VIS ID
TVIS44026581
Fusion event
HTLV-1-ANO3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
26671987/26650440 (Hg38)
End
26671987/26650440 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11D
Target gene
ANO3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-18a-3p ; hsa-mir-186-5p ; hsa-mir-26a-5p
Nearest miRNA
hsa-mir-210/Upstream/3231250; hsa-let-7a-2/Downstream/864530;
Nearest TSS
ENST00000527297/Upstream/78207; ENST00000318627/Downstream/71559;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/318175, chr11-CpG: 29/Downstream/712632
Upstream sequence
TAATTAAGAATTCAAGGTTTAGAATCAGATAGATGCGTGTTTGAATCTAGGTTCCGAGGGCAGTCCTTCTTAACATGTggtctgcagatctccttcaggg
Downstream sequence
gtccatgaagtcgatgcgatttttatactgaaattaagatatcatttgcccttttcatatattgacattttccctagtgatccaaaaatattggtgaata
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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