Basic Information
VIS ID
TVIS44026598
Fusion event
HTLV-1-PRR5L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
GRCh37/hg19
Start
36480890/36459340 (Hg38)
End
36480890/36459340 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRR5L
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-502-5p ; hsa-mir-27b-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125
Nearest miRNA
hsa-mir-1343/Upstream/449136; hsa-let-7a-2/Downstream/7100316;
Nearest TSS
ENST00000527297/Upstream/4051; ENST00000529126/Downstream/37170;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/81492, chr11-CpG: 82/Downstream/50277
Upstream sequence
AGAGGAGCATGAGTTGGGGGACTTCTCTGGGACCAAGGGACCCAGCCTTGTCATGGTGCTTACTCTATTCCAAACTCTGTGCATGTTTCTGCCCTAGCGC
Downstream sequence
AGCCCATGTGAAGGTGGGAGAGCAGAGGCCCTGGGAGCTGGGGTGCTGCTGTCAGATTTGCTTCCTCTCTTGGGACTCTACTCCCGAGGCTTCAGTTATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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