Basic Information
VIS ID
TVIS44026627
Fusion event
HTLV-1-OR51B5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
5421164/5399934 (Hg38)
End
5421164/5399934 (Hg38)
Orient
+
Location type
Intronic
Target gene
OR51B5
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-210/Upstream/1543793; hsa-let-7a-2/Downstream/1834832;
Nearest TSS
ENST00000527297/Upstream/10557; ENST00000300778/Downstream/22177;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/791634, chr11-CpG: 32/Downstream/834604
Upstream sequence
GCAGAGGAGGAGAGACTCTAGTTTCAAGTATCAGTCAAGATTTGTTTCTTCCAATATCCGGTTATTTGAGGTGTGGCAGGCAAGATACAGGGTGCAGTGG
Downstream sequence
GATCAAGGATTCAGTAAGGCAGCACACGGGAAGAACAGCTGCTCAATCCAGAGGCAGATCAATATTTGGTCTATTTAAAGAACTAAGAAGGCTATGTTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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