Basic Information
VIS ID
TVIS44026634
Fusion event
HTLV-1-OSBP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59372308/59604835 (Hg38)
End
59372308/59604835 (Hg38)
Orient
-
Location type
Intronic
Target gene
OSBP
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-505-3p ; hsa-mir-365a-3p ; hsa-mir-6878-5p ; hsa-mir-2467-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-5197-3p ; hsa-mir-6507-5p ; hsa-mir-3157-5p ; hsa-mir-4671-3p ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-6077 ; hsa-mir-6770-5p ; hsa-mir-3179 ; hsa-mir-1252-5p ; hsa-mir-4691-3p ; hsa-mir-203a-3p ; hsa-mir-7852-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-3154 ; hsa-mir-5680 ; hsa-mir-4422 ; hsa-mir-6835-3p
Nearest miRNA
hsa-mir-129-2/Upstream/9677; hsa-let-7a-2/Downstream/604236;
Nearest TSS
ENST00000527297/Upstream/3979; ENST00000531108/Downstream/11309;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/43801, chr11-CpG: 68/Downstream/10604
Upstream sequence
tcccagctactcagaaggctgaggagtgagactcacttgagcctgggtgctcaaggctgcagtgagctatgatggtgccactgcactccagcctgggtga
Downstream sequence
gagagcaatactctgtctctaaaaaaaaaagaaaaaggccgagcacagtggctcatgtctgtaatcccagcactttgggaggcctaggcaggtggatcac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate