Basic Information
VIS ID
TVIS44026638
Fusion event
HTLV-1-EML3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
62380043/62612571 (Hg38)
End
62380043/62612571 (Hg38)
Orient
+
Location type
UTR5
Target gene
EML3
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-129-2/Upstream/45500; hsa-let-7a-2/Downstream/177244;
Nearest TSS
ENST00000527297/Upstream/41; ENST00000525947/Downstream/170;
Nearest CpG islands
chr11-CpG: 103/Target, None/Upstream, None/Downstream
Upstream sequence
GCTCCGAGCGGCGGCGGCGGAGGAGGCGTCTAAGCCGCGGGGGCCACGGCCGGGGAGAGGGGAAGGGGAAGCACCCCGGGGCGCGCGCGAAGGGCGCCGT
Downstream sequence
ACCACCACCCCGAGGGGGCGCTGTCGGGCGCGGGGAAGGGGCCTGGAGGGGGCGCTGTGGGCCCGGGGCCGCAGTCTCCAGACCCCCCCGGGCCCTCGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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