Basic Information
VIS ID
TVIS44026640
Fusion event
HTLV-1-RCOR2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
63681837/63914365 (Hg38)
End
63681837/63914365 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
RCOR2
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-129-2/Upstream/1121594; hsa-let-7a-2/Downstream/427484;
Nearest TSS
ENST00000527297/Upstream/1409; ENST00000545161/Downstream/2479;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2199, chr11-CpG: 80/Downstream/1906
Upstream sequence
TCTTGGGATCTGCAGGATCGGGCTCTCCCTCACTCACGCCTCCTCGACCCTCTTCGAGCTCATCACTGCTGACACAGGGGCCAGGGAGGGAATGAGGCAG
Downstream sequence
CTGCCAGGAGCTCTACCTACCCCCATGCCCAGTGCTTGCTCCTGCCCCCACCTGTCTTCTTTGTCCTTGCGGCCCCCCAGCCGCCGGGCCTGTCTGTCCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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