Basic Information
VIS ID
TVIS44026641
Fusion event
HTLV-1-RASGRP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64495452/64727980 (Hg38)
End
64495452/64727980 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
RASGRP2
Nearest miRNA
hsa-mir-1237/Upstream/359277; hsa-let-7a-2/Downstream/150543;
Nearest TSS
ENST00000527297/Upstream/4792; ENST00000594089/Downstream/7286;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/4306, chr11-CpG: 320/Downstream/13981
Upstream sequence
TTTGTCAGCGCAGTTTGCTTAAATGTCAATTTTGTGTGTATTTCACATTTTAGACCCCAGCACTTCTGGAAGGCTCAATGCAAATGGATTTATCTTTTCT
Downstream sequence
ATTTTTGAGGATGTATGCCCTGTGCCTGCCTCTGTTTTTTGAGGACTTATGCCAACCCAAACAGTTGTGATCAACTACCTTAGACCCCAGTTTAACATAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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