Basic Information
VIS ID
TVIS44026646
Fusion event
HTLV-1-RRP8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
6606649/6585419 (Hg38)
End
6606649/6585419 (Hg38)
Orient
-
Location type
Intronic
Target gene
RRP8
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-3978 ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-3928-3p ; hsa-mir-100-3p ; hsa-mir-578 ; hsa-mir-4764-5p ; hsa-mir-323b-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-1246 ; hsa-mir-8076 ; hsa-mir-5583-3p ; hsa-mir-6507-3p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-4999-3p ; hsa-mir-6771-3p
Nearest miRNA
hsa-mir-210/Upstream/2729278; hsa-let-7a-2/Downstream/649347;
Nearest TSS
ENST00000527297/Upstream/16714; ENST00000534565/Downstream/15885;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/13866, chr11-CpG: 48/Downstream/17903
Nearby gene
DNHD1(+13395) ;
Upstream sequence
ctgaggcaggtggactgctcgaggtcaggagttcgagaccaacctggccaacatggtgaaaccccatctctactaaaaatacaaaaactagctgggcgtg
Downstream sequence
gtggcaggtgcctgtaatcctagctacttgggagtctgaggtaggagaatcgcttgaacctgagaggtgggggttgcagtgagccaagattgtgccactg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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