Basic Information
VIS ID
TVIS44026655
Fusion event
HTLV-1-ANO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
70011885/70165779 (Hg38)
End
70011885/70165779 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H ; FRA11A
Target gene
ANO1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-381-3p
Nearest miRNA
hsa-mir-10392/Upstream/1082521; hsa-let-7a-2/Downstream/118176;
Nearest TSS
ENST00000527297/Upstream/417; ENST00000525494/Downstream/4186;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9897, chr11-CpG: 18/Downstream/11172
Upstream sequence
GCACTAGAAGCAGGGAGAGAAGGAGGACACAGAGGGAAGGTGGGGCAAAAGCCACCCCAggccaggcatggtggctgacgcctgtaatcccagcactttg
Downstream sequence
ggaagctgaggcagaaggaccatttgagcctaggaaatcaagaccagcctaagcacaaagcgagactgcacctctacaaaaaaataaaaagttagccagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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