Basic Information
VIS ID
TVIS44026665
Fusion event
HTLV-1-ATG16L2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
72525784/72814739 (Hg38)
End
72525784/72814739 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
ATG16L2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10392/Upstream/31147; hsa-let-7a-2/Downstream/1584498;
Nearest TSS
ENST00000527297/Upstream/307; ENST00000451353/Downstream/1148;
Nearest CpG islands
chr11-CpG: 111/Target, None/Upstream, None/Downstream
Upstream sequence
TCCTCCGCCTGTGACCCGAGTGCGCTGTGCCTTATGCCTTGAGCCTGTGCGTTACGCCCATCCCGACTGCCAGGACTCCGCCCCTTGCCATCCAGGCTCT
Downstream sequence
GGTTAGAACCTGGACGAGCCCCTCCTGGTCCCCCTGCCCTCGTCGCCCCTCAGGACGGGCTCTGCCTCCCACAAGCTGGGCTTCCGAGACGCAAGTGCGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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