Basic Information
VIS ID
TVIS44026666
Fusion event
HTLV-1-C2CD3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
73733854/74022809 (Hg38)
End
73733854/74022809 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
C2CD3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10392/Upstream/1239217; hsa-let-7a-2/Downstream/376428;
Nearest TSS
ENST00000527297/Upstream/13374; ENST00000542710/Downstream/11100;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/39052, chr11-CpG: 58/Downstream/148045
Upstream sequence
TTAACAAAATCAGGAAGCTGTCCCAGTAAAGAGTTACTTCATCACAAGAGGGAAGAGAAAGCAGGGGCAGCGGAACTTGATTGATTTATAATGAATTTGG
Downstream sequence
AACTGCAAATGGATCGCTGTGCTGCAGTCCTGCTAAACCAGCCATCGTTCTCACCCCTTTTCTTTTTGCAGAGGCGACAGCCAGAAGTTGAAGTAGCATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate