Basic Information
VIS ID
TVIS44026667
Fusion event
HTLV-1-WNT11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.5
Reference genome
GRCh37/hg19
Start
75913305/76202261 (Hg38)
End
75913305/76202261 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
WNT11
miRNAs that regulate target gene
hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p
Nearest miRNA
hsa-mir-10392/Upstream/867075; hsa-let-7a-2/Downstream/3199761;
Nearest TSS
ENST00000527297/Upstream/11536; ENST00000530460/Downstream/4146;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/7387, chr11-CpG: 407/Downstream/3966
Nearest cancer related gene
WNT11(TSG, No orient, 0)
Upstream sequence
CCCCCATCAGCGCCACCCAGAATGTAGCCTGGCAGCTGCCCACCCAGGGAGAGAGATGGGGTGAGGTCAACAGATGGCGATGAGAGAGACCCTGATGCCC
Downstream sequence
ACATCTGTGCTTCTGGGATGAGGAGGATGCTGATGAGGGCTGCGGGCTGGCTTAGGGACTCAGTCTTGCCCTGGAATCCCCATGCTTCTGCATCTGTGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate