Basic Information
VIS ID
TVIS44026670
Fusion event
HTLV-1-AAMDC integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
77577634/77866588 (Hg38)
End
77577634/77866588 (Hg38)
Orient
-
Location type
Intronic
Target gene
AAMDC
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10392/Upstream/2531402; hsa-let-7a-2/Downstream/1535434;
Nearest TSS
ENST00000527297/Upstream/15984; ENST00000529666/Downstream/3503;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/45372, chr11-CpG: 36/Downstream/127966
Upstream sequence
TCTTTCATTGCTTTGTACATGACACTGTGAGCCTGCAGTAAAGCAGCAGCAGCCCAGTTCATCACTTGAGTTCCATTGATCCAGCCACTCCAATGGGCTG
Downstream sequence
TGGCTGTCTCCAGTCTAATCTCCAGAGGATTATGGGTTTGTAGTCTCCTATGACCTTACACTTGGATTTCCAGCAGTCAGTGGCCTCTTGTTTCATTTTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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