Basic Information
VIS ID
TVIS44026689
Fusion event
HTLV-1-PANX1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q21
Reference genome
GRCh37/hg19
Start
93867464/94134298 (Hg38)
End
93867464/94134298 (Hg38)
Orient
-
Location type
Intronic
Target gene
PANX1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-192-5p ; hsa-mir-125a-5p ; hsa-mir-10a-5p ; hsa-mir-890 ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n
Nearest miRNA
hsa-mir-10392/Upstream/400534; hsa-let-7a-2/Downstream/332197;
Nearest TSS
ENST00000527297/Upstream/5369; ENST00000506309/Downstream/103852;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/4691, chr11-CpG: 57/Downstream/266762
Upstream sequence
ATCTGTGTGGCTTGGGTACCCTATGGGTGTCACCTTGTGCAAGCTGCTGGGAGACAGTGCCTTGAGGCCCTTCATTTCTAACACATCTACTCTCAGATGC
Downstream sequence
CTCTAGAAGTGCTGCACATTTCATTGATGGGGGGAGAGGTTTAGGAAATGGCTGGGCGACAGCTTTGTGTAGAATATAAGCATGATTGCATGACGTGACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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