Basic Information
VIS ID
TVIS44026702
Fusion event
HTLV-1-IGF1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.2
Reference genome
End
102868768/102474990 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-27a-3p ; hsa-mir-483-3p ; hsa-let-7e-5p ; hsa-mir-190b ; hsa-mir-299-3p ; hsa-let-7i-5p ; hsa-mir-199a-3p ; hsa-mir-190a-5p ; hsa-mir-29a-3p ; hsa-mir-6739-3p ; hsa-mir-576-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-7641 ; hsa-mir-539-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-302a-5p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-6771-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-211-3p ; hsa-mir-5011-5p ; hsa-mir-4662a-3p ; hsa-mir-1305 ; hsa-mir-4753-3p ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-130b-5p ; hsa-mir-3065-5p ; hsa-mir-10a-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6514-3p ; hsa-mir-6765-5p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-7160-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6087 ; hsa-mir-3197 ; hsa-mir-4649-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-574-5p ; hsa-mir-297 ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-133a-3p ; hsa-mir-18b-5p ; hsa-mir-28-5p ; hsa-mir-603 ; hsa-mir-130b-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-129-5p ; hsa-mir-128-3p ; hsa-mir-26a-5p
Nearest miRNA
hsa-let-7i/Upstream/2285041; hsa-mir-1178/Downstream/1455435;
Nearest cancer related gene
IGF1(TSG, No orient, 0)
Upstream sequence
GCTGTTGACTTTCTAATCACCTAAGAGCTATTTAAGAGATAAGTGATTCTGTACTTGTCAGAGACCCTTTTCCAGATGGTGATATCATTGATGGGTCCCG
Downstream sequence
GAGAAGAACTATGCCAAAAGAGAGCAACAACAAAAAAATCAAGGTCAAGTGGCATAGAGGGCAAATCAGTATGGCATTTCAGTTTGCATTTAGAGACAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate