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TVIS44026702
Basic Information
VIS ID
TVIS44026702
Fusion event
HTLV-1-IGF1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
102868768/102474990 (Hg38)
End
102868768/102474990 (Hg38)
Orient
+
Location type
Intronic
Target gene
IGF1
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-27a-3p
;
hsa-mir-483-3p
;
hsa-let-7e-5p
;
hsa-mir-190b
;
hsa-mir-299-3p
;
hsa-let-7i-5p
;
hsa-mir-199a-3p
;
hsa-mir-190a-5p
;
hsa-mir-29a-3p
;
hsa-mir-6739-3p
;
hsa-mir-576-5p
;
hsa-mir-7156-5p
;
hsa-mir-4273
;
hsa-mir-7641
;
hsa-mir-539-5p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-7847-3p
;
hsa-mir-6880-5p
;
hsa-mir-6851-5p
;
hsa-mir-3689d
;
hsa-mir-6499-3p
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-6134
;
hsa-mir-302a-5p
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-6771-3p
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-211-3p
;
hsa-mir-5011-5p
;
hsa-mir-4662a-3p
;
hsa-mir-1305
;
hsa-mir-4753-3p
;
hsa-mir-421
;
hsa-mir-505-3p
;
hsa-mir-7159-5p
;
hsa-mir-130b-5p
;
hsa-mir-3065-5p
;
hsa-mir-10a-3p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6514-3p
;
hsa-mir-6765-5p
;
hsa-mir-7977
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-7160-5p
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-6087
;
hsa-mir-3197
;
hsa-mir-4649-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-574-5p
;
hsa-mir-297
;
hsa-mir-6867-5p
;
hsa-mir-4711-3p
;
hsa-mir-223-5p
;
hsa-mir-567
;
hsa-mir-133a-3p
;
hsa-mir-18b-5p
;
hsa-mir-28-5p
;
hsa-mir-603
;
hsa-mir-130b-3p
;
hsa-mir-98-5p
;
hsa-mir-26b-5p
;
hsa-mir-129-5p
;
hsa-mir-128-3p
;
hsa-mir-26a-5p
Nearest miRNA
hsa-let-7i/Upstream/2285041; hsa-mir-1178/Downstream/1455435;
Nearest TSS
ENST00000382841/Upstream/59244;
ENST00000266744/Downstream/3661;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/354819
,
chr12-CpG: 38/Downstream/349352
Nearest cancer related gene
IGF1
(TSG, No orient, 0)
Upstream sequence
GCTGTTGACTTTCTAATCACCTAAGAGCTATTTAAGAGATAAGTGATTCTGTACTTGTCAGAGACCCTTTTCCAGATGGTGATATCATTGATGGGTCCCG
Downstream sequence
GAGAAGAACTATGCCAAAAGAGAGCAACAACAAAAAAATCAAGGTCAAGTGGCATAGAGGGCAAATCAGTATGGCATTTCAGTTTGCATTTAGAGACAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HTLV-1 carrier#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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